Efficacy and safety of commercialized fecal microbiota transplant for the treatment of recurrent Clostridioides difficile infection


      • Commercialized fecal microbiota transplant (cFMT) is an effective and safe therapy for recurrent CDI.
      • Cure rates with oral cFMT and colonoscopy were found to be over 80%.
      • There were no serious adverse events reported as a result of cFMT.


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        • Youngster I.
        • Russell G.H.
        • Pindar C.
        • Ziv-Baran T.
        • Sauk J.
        • Hohmann E.L.
        Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection.
        JAMA. 2014; 312: 1772-1778
        • Cammarota G.
        • Ianiro G.
        • Gasbarrini A.
        Fecal microbiota transplantation for the treatment of Clostridium difficile infection: a systematic review.
        J Clin Gastroenterol. 2014; 48: 693-702
        • Martinez C.
        • Edwards J.
        • Hassoun A.
        Commercialized fecal microbiota transplantation provides efficacious treatment of Clostridium difficile infection.
        Inf Disp. 2018; 50: 864-867
        • Bouza E.
        Consequences of Clostridium difficile infection: understanding the healthcare burden.
        Clin Microbiol Infect. 2012; 18: 5-12
        • Marchesi J.R.
        • Adams D.H.
        • Fava F.
        • et al.
        The gut microbiota and host health: a new clinical frontier.
        Gut. 2016; 65: 330-339
        • Rubin T.A.
        • Gessert C.E.
        • Aas J.
        Stool transplantation for older patients with Clostridium difficile infection.
        J Am Geriatr Soc. 2009; 57: 2386
        • Postigo R.
        • Kim J.H.
        Colonoscopic versus nasogastric fecal transplantation for the treatment of Clostridium difficile infection: a review and pooled analysis.
        Infection. 2012; 40: 643-648
        • Sofi A.A.
        • Silverman A.L.
        • Khuder S.
        • Garborg K.
        • Westerink J.M.A.
        • Nawras A.
        Relationship of symptom duration and fecal bacteriotherapy in Clostridium difficile infection – pooled data analysis and a systematic review.
        Scand J Gastroenterol. 2013; 48: 266-273
        • Gough E.
        • Shaikh H.
        • Manges A.R.
        Systematic review of intestinal microbiota transplantation (fecal bacteriotherapy) for recurrent Clostridium difficile infection.
        Clin Infect Dis. 2011; 53: 994-1002